Braingeneers
We are members of the Braingeneers group, a research consortium that brings together neuroscientists, geneticists and engineers to study the unique specializations of the human brain. Other members of the group include laboratories at UC Santa Cruz (Haussler, Teodorescu, Salama, Sharf), UC San Francisco (Pollen, Nowakowski), UC Santa Barbara (Kosik) and Washington University in St. Louis (Hengen)
SSPsyGene
We are co-leading the Data Resource and Coordination Center (DRACC) for the SSPsyGene Consortium. This consortium is an NIMH initiative to systematically characterize the most important 250 genes in neuropsychiatric disorders. Other members of the DRACC are labs in UC Santa Cruz (Haussler, Haeussler, Paten) and UC San Francisco (Nowakowski). Other members of the consortium are labs at UC Los Angeles (Geschwind, Novitch, Aharoni, Bhaduri, Damoiseaux, Golshani, Kim, Luo, Wells), the Broad Institute (Nehme, Farhi, Levin), MIT ( Fraenkel), NorthShore (Duan, Zhang, Sanders), Rutgers (Pang, Mulle, Hart, Li, Pato, Kreimer), Baylor (Tolias), University of Chicago (He), Yale (Hoffman, Fan, Brennand, Huckins, Wang), the Scripps Institute (Jin), Penn State (Kim, Paul), the Jackson Laboratories (Kumar), WashU (Dougherty, Gabel, Kravitz, Mitra, Maloney).
CIRM ReMIND
We participate in three multi-institutional teams funded through the CIRM ReMIND program. The first, led by Alex Pollen at UCSF, focuses on deep phenotyping of human brain organoid models of autism spectrum disorder to unravel disease heterogeneity and develop biomarkers and treatments, and brings together laboratories from UCSF (Sherr, Kampmann, and Sato), UCSC (Salama and Teodorescu), and UC Berkeley (Shaffer and Bateup). The second, led by Aparna Bhaduri at UCLA, addresses neurovascular metabolism in neurodevelopmental and neuropsychiatric disorders through a collaboration spanning UCLA (Christofk, Kornblum, and Zeiger) and UCSF (Crouch). The third, led by Dan Geschwind at UCLA, aims to advance therapeutic discovery through multimodal analyses of genetic and cellular mechanisms in neuropsychiatric disorders, with participation from five UCLA laboratories (Wells, Novitch, Damoiseaux, Golshani, and Pimentel).